Articles from PHC Corporation

PHC Corporation’s Biomedical Division (Head Office: Chiyoda-ku, Tokyo; President: Nobuaki Nakamura; hereinafter “PHCbi”), a global provider of laboratory sample storage and cell cultivation solutions and subsidiary of PHC Holdings Corporation (Head Office: Chiyoda-ku, Tokyo), today announced the launch of its new cell expansion system LiCellGrow™ (*1) for research use in Japan and other select countries worldwide(*2). The system is designed to improve quality and efficiency in the production of new advanced therapies by allowing therapy developers to visualize metabolic changes in cells in real time and automatically control culture conditions.

PHC Corporation (Headquarters: Chiyoda-ku, Tokyo; President: Nobuaki Nakamura; hereafter referred to as "PHC"), a subsidiary of PHC Holdings Corporation (Headquarters: Chiyoda-ku, Tokyo; President: Kyoko Deguchi), and Cyfuse Biomedical K.K. (Headquarters: Minato-ku, Tokyo; CEO: Shizuka Akieda; hereafter referred to as "Cyfuse") announce the successful development of a new production technology(*1) for the commercialization of the field of regenerative and cell therapy. This achievement is the result of a strategic collaboration(*2) and joint research between the two companies.

PHC Corporation has signed a Master Collaboration Agreement with CCRM to work together on the development of primary T-cell(*1) expansion culture processes that will seek to accelerate the manufacturing of cell and gene therapy (CGT) products. This joint initiative will integrate “LiCellGrowTM(*2), PHC’s cell expansion system under development, with CCRM’s deep knowledge of regenerative medicine and biomanufacturing to establish new culture processes to improve cell culture efficiency and quality for CGTs.

The Biomedical Division of PHC Corporation (Headquarters: Chiyoda-ku, Tokyo, Japan; President: Nobuaki Nakamura), has received a 2024 Innovation Award from The Analytical Scientist1 for its live cell metabolic analyzer, LiCellMoTM. LiCellMo, launched for research use in Japan in September and the United States, UK, EU, China and other Asian select geographies in October2, provides continuously measured data on key cellular metabolic pathways3, giving researchers a precise picture of previously unobservable changes in the state of cells over time and allowing them to make more informed research decisions. This will help contribute to novel research findings and important advances in therapies. It is designed to reveal cellular metabolic mechanisms and improve the reproducibility and quality of cell cultures in the development of manufacturing processes for cell and gene therapy products.

PHC Corporation Biomedical Division (headquarters: Chiyoda-ku, Tokyo, President: Nobuaki Nakamura; hereafter Biomedical Division) announced today the commercial launch of LiCellMo, a live cell metabolic analyzer that allows researchers to visualize metabolic(*1) changes in cell cultures, providing a more complete picture of cell activity for research uses in cell and gene therapies (CGT). LiCellMo uses PHC’s proprietary high-precision In-Line monitoring technology(*2), which enables continuous measurement of cellular metabolites in culture medium without needing to interrupt the experiment for sampling. LiCellMo will be launched in Japan in September, followed by a launch in other select geographies in October.

PHC Corporation (headquarters: Minato-ku, Tokyo, President: Nobuaki Nakamura, hereafter PHC) and NovaScan, Inc. (headquarters: Chicago, Illinois, CEO: Craig Davis, hereafter NovaScan) announce the launch of a collaboration through which they will seek to explore the feasibility of MarginScanTM, an investigational “ex vivo” (outside the body) medical device that will seek to support physicians in detecting non-melanoma skin cancers (NMSC).

The In Vitro Diagnostics Division of PHC Corporation (hereafter, PHC IVD), a provider of medical devices and diagnostics, today announced that it has received European Union Medical Devices Regulation (EU-MDR) certification for a motorized drug injection device that delivers anti-inflammatory medications called tumor-necrosis factor (TNF) inhibitors. The device, called APP-1000*1, is designed to provide simple, precise, and monitored drug injections in the home setting for conditions including rheumatoid arthritis. The EU-MDR certification clears the way for future distribution of the device in approximately 20 countries including EU countries, Switzerland, and South America.